论文部分内容阅读
以辣根过氧化物酶（PO）和抗-PO作为免疫沉淀中的抗原和抗体，用光电比色法，对78例小儿肾脏疾病血清补体对免疫沉淀的抑制作用（IIPC）进行了研究，并同时检测补体成分C3、C4。结果，正常对照IIPCOD值为0．505±0．085，急性肾小球肾炎（0．137±0．108）显著降低（P＜0．001）；慢性肾小球肾炎（0．470±0．053）改变不明显（P＞0．05）；肾病综合征（0．401±0．038）明显低下（P＜0．05）。IIPC低下的发生率依次为急性肾小球肾炎（83％）、肾病综合征（43％）、慢性肾小球肾炎（32％）。表明小儿肾小球疾病时IIPC大多降低并与疾病的活动性有关。因此认为IIPC低下在肾脏病的发生和发展中起一定作用。
Using immunoprecipitation of horseradish peroxidase (PO) and anti-PO as antigens and antibodies, the immunoprecipitation (IIPC) of 78 children with renal disease was studied by photoelectric colorimetry. At the same time detect complement components C3, C4. As a result, the IIPCOD value of the normal control group was 0.505 ± 0.085, that of the acute glomerulonephritis group (0.137 ± 0.108) was significantly lower (P <0.001), and that of the chronic glomerulonephritis group (0.470 ± 0 .053) had no significant change (P> 0.05); nephrotic syndrome (0.401 ± 0.038) was significantly lower (P <0.05). The incidence of low IIPC followed by acute glomerulonephritis (83%), nephrotic syndrome (43%), chronic glomerulonephritis (32%). That pediatric glomerular disease mostly lower IIPC and disease activity related. So IIPC low in the occurrence and development of kidney disease play a role.