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Since early 80s of last century,Chinese herbal medicines focused on the isolation and structural identification of active/chemical compounds have being investigated,started the journey from Henan College of Traditional Chinese Medicine.After one year (1985～ 1986) advanced study in Prof.Jingxi Xies laboratory in the Institute of Materia Medica,Chinese Academy of Medical Sciences in Beijing,further studies in Prof.Takuo Okudas laboratory,Okayama University,Japan as a guest researcher from 1988 to 1992 opened a fresh and amazing gate of tannin chemistry.Near 10 years＇investigation of tannins and related polyphenols from Chinese herbal medicines,supported by National Natural Science Foundation of China and other grants,some typical herbs containing tannins and related polyphenols as major active components have been in-depth studied,such as Loropetalum chinense,Epilobium angustifolium,Rhodmyrtus tomentosa,Lythrum salicaria,Epilobium pyrricholophum,Rodgersia podoph ylla,Punica granatum,Euphorbia humifusa,and Cornus of ficinalis etc.Hundreds of diversified tannins and related polyphenols have been isolated including monomer,dimmer,trimer of ellagitannins and C-glycosidic tannins etc.