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目的评价介入治疗对于动脉粥样硬化性肾动脉狭窄(ARAS)血压、肾功能方面的近中期疗效。方法对2009年4月—2012年4月本院收治的56例ARAS患者行介入治疗,随访观察术后1周、1个月、6个月、12个月的血压、降压药物及肾功能变化情况。结果接受介入手术治疗的患者共有56例,其中双侧肾动脉狭窄患者9例,单侧肾动脉狭窄患者47例。手术成功率98.2%,手术后无严重并发症。术后对所有患者均进行了随访,随访中没出现支架移位,有5例出现支架内再狭窄。至随访结束时,高血压获益率69.1%,肾功能改善获益率85.5%。随访过程中血压,降压药物使用量与手术前比较明显降低,差异有统计学意义(P<0.05)。讨论ARAS患者介入治疗手术成功率高,近期和中期在控制血压,改善肾功能方面有重要作用。
Objective To evaluate the effect of interventional therapy on blood pressure and renal function in atherosclerotic renal artery stenosis (ARAS). Methods Fifty-six ARAS patients admitted to our hospital from April 2009 to April 2012 were included in this study. Blood pressure, antihypertensive drugs and renal function were observed at 1 week, 1 month, 6 months and 12 months after operation. Changes. Results A total of 56 patients underwent interventional surgery, including 9 patients with bilateral renal artery stenosis and 47 patients with unilateral renal artery stenosis. Surgical success rate of 98.2%, no serious complications after surgery. All patients were followed up after surgery, no follow-up stent shift, 5 cases of stent restenosis. By the end of follow-up, the benefit rate of hypertension was 69.1%, and the benefit rate of renal function improvement was 85.5%. During follow-up, blood pressure and antihypertensive drugs significantly decreased compared with that before operation, with significant difference (P <0.05). Discussion ARAS patients with high success rate of interventional surgery, the recent and mid-term in the control of blood pressure, improve renal function has an important role.