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目的 :探讨婴儿肝炎综合征及胆道闭锁与CMV感染的关系及其治疗方法。方法 :采用回顾性调查方法 ,对 38例婴儿黄疸患儿的临床与CMV感染的关系及其治疗情况进行分析。结果 :38例婴儿黄疸患儿中CMV感染率为5 0 0 % (19 38) ,高于 40例非黄疸婴儿中的CMV感染率 (7 5 % ;3 40 ) ,P <0 0 0 1;2 9例婴儿肝炎综合征中CMV感染率为 44 8% (13 39) ,与 9例临床诊断为胆道闭锁病儿的CMV感染率 (6 6 6 % ;6 9)比较无统计学差异 ,P >0 0 5。本组由99mTC -EHIDA肝核素扫描诊断为胆道闭锁的 9例病儿 ,经内科保守治疗的有效率达 88 8% (8 9)。结论 :CMV感染是婴儿肝炎综合征及胆道闭锁的重要原因 ,胆道闭锁可能是婴儿肝炎综合征进一步发展的结果 ;部分经99mTC -EHIDA肝核素扫描诊断为胆道闭锁的病儿 ,经内科保守治疗可以达到治疗的目的
Objective: To investigate the relationship between infant hepatitis syndrome and biliary atresia and CMV infection and its treatment. Methods: The retrospective investigation of 38 cases of infant jaundice clinical and CMV infection and its treatment were analyzed. Results: The infection rate of CMV in 38 infants with jaundice was 500% (19 38), higher than that of 40 infants without jaundice (75%; 340), P <0.01; The infection rate of CMV in 29 cases of infantile hepatitis syndrome was 44.8% (13 39), which was not significantly different from that of 9 cases of clinically diagnosed as biliary atresia (66.6% vs 69.6%). P > 0 0 5. Nine patients diagnosed as biliary atresia by 99mTC-EHIDA were proved to be 88.8% (89%) conservative in medical treatment. Conclusion: CMV infection is an important cause of infantile hepatitis syndrome and biliary atresia. Biliary atresia may be the result of the further development of infantile hepatitis syndrome. Some patients diagnosed as biliary atresia with 99mTC -EHIDA scan by conservative medical treatment Can achieve the purpose of treatment