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目的对健康体检中青年男性进行骨密度(BMD)检测分析,研究中青年男性吸烟与BMD改变的关系。方法用美国GE Lunar公司生产的Prodigy型双能X线吸收法(DXA),对来院进行常规体检的中青年男性进行BMD检测,分别测量正位L1~L4及一侧股骨颈部BMD值,共498例,年龄28~50岁。所有受检者均进行问卷调查,内容包括生活习惯、健康状况、药物治疗情况。经筛选后每天吸烟20支以上,烟龄达10年以上者83例入选吸烟组,另选82例无不良生活习惯的男性作为对照组;根据所测BMD值进行回顾性分析。结果 (1)吸烟组L1~L4BMD值低于对照组[(1.083±0.096)g/cm2vs(1.167±0.104)g/cm2,P<0.01],股骨颈BMD值低于对照组[(0.876±0.087)g/cm2vs(0.921±0.093)g/cm2,P<0.01]。(2)烟龄10~20年组L1~L4BMD值高于烟龄≥21年组[(1.153±0.106)g/cm2vs(1.130±0.098)g/cm2,P<0.01],股骨颈BMD值高于烟龄≥21年组[(0.897±0.092)g/cm2vs(0.855±0.082)g/cm2,P<0.01],说明吸烟的烟龄越长其BMD值越低。结论长期吸烟可导致男性骨量丢失,预防骨质疏松要对中青年人进行骨质疏松相关知识的宣教,戒烟有利于骨骼健康。
Objective To investigate bone mineral density (BMD) in middle-aged and healthy young men and investigate the relationship between smoking and BMD in young men. Methods BMD was measured by Prodigy dual energy X-ray absorptiometry (DXA) by GE Lunar, USA. The BMD was measured in L1 to L4 anteroposterior and femoral neck BMD 498 cases, aged 28 to 50 years old. All subjects were surveyed, including life habits, health status, drug treatment. After screening, smoking more than 20 cigarettes a day, smoking for more than 10 years, 83 cases were enrolled in the smoking group, another 82 cases without bad habits of men as a control group; according to the measured BMD value for retrospective analysis. Results (1) The values of L1 ~ L4 BMD in smoking group were significantly lower than those in control group [(1.083 ± 0.096) g / cm2 vs (1.167 ± 0.104) g / cm2, P <0.01] ) g / cm2 vs (0.921 ± 0.093) g / cm2, P <0.01]. (2) The values of L1 ~ L4BMD in 10-20 years old group were significantly higher than those of 21 years old group (1.153 ± 0.106 g / cm2 vs 1.130 ± 0.098 g / cm2, P <0.01) (0.897 ± 0.092) g / cm2 vs (0.855 ± 0.082) g / cm2, P <0.01], indicating that the longer the smoking age, the lower the BMD. Conclusion Long-term smoking can lead to bone loss in men and prevention of osteoporosis. It is necessary to educate young and middle-aged people about osteoporosis, and smoking cessation is beneficial to bone health.