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氟喹酮类为新型高效抗菌药物,对革兰阴性杆菌和球菌,很多革兰阳性菌(包括肠球菌及耐甲氧青霉素金葡菌)均具抗菌作用。其抗菌活性强,口服吸收好,临床效果佳,副作用小。本类药物不仅对常见的尿路、呼吸道、肠道、皮肤、外科等各种感染具良好疗效,而且对某些难治性感染,如丙氟哌酸对绿脓杆菌感染和严重全身感染,也具相当效果。本类药物对多重耐药细菌的活性也值得重视,将有可能成为临床治疗多重耐药菌感染的有效武器。
Fluoroquinolone is a new and highly effective antibacterial drug that has antibacterial activity against Gram-negative bacilli and cocci, and many Gram-positive bacteria (including enterococci and methicillin-resistant Staphylococcus aureus). Its antibacterial activity, oral absorption, good clinical effect, side effects. This class of drugs not only for the common urinary tract, respiratory tract, intestinal, skin, surgical and other infections with good effect, but also for some refractory infections, such as propylene norfloxacin against Pseudomonas aeruginosa infection and severe systemic infection, Also have a considerable effect. The activity of multidrug-resistant bacteria of this kind of medicine is also worth paying attention to, it will be possible to become an effective weapon for clinical treatment of multi-drug resistant bacteria.