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肿瘤细胞的浸润转移是一个复杂的、多步骤的恶性行为过程 ,包括粘附、降解、移动三步。这个过程与机体及肿瘤细胞多种生物学改变有密切关系。现就胃癌恶性行为的主要生物学基础综述如下。1 细胞外基质成分肿瘤细胞通过其膜上的特殊受体与细胞外间质 (ＥＣＭ)成分结合 ,进而产
Infiltration and metastasis of tumor cells is a complex and multi-step malignant process including adhesion, degradation and migration. This process and the body and tumor cells a variety of biological changes are closely related. The main biological basis of malignant behavior of gastric cancer are summarized below. 1 Extracellular matrix components Tumor cells bind to extracellular matrix (ECM) components through specific receptors on their membranes and thus produce