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目的分析无创机械通气和有创机械通气治疗慢性阻塞性肺疾病(COPD)并发肺性脑病的疗效。方法回顾性分析西安医学院第一附属医院呼吸内科2010年1月至2011年6月收治的COPD合并肺性脑病患者的临床资料,选取采用机械通气治疗的患者,根据机械通气的方式不同分为无创组和有创组,分析两组的治疗效果。结果两组治疗后在血气分析上均明显改善,但有效率和病死率比较差异无统计学意义,同时无创组的并发症明显低于有创组。结论对COPD合并肺性脑病的患者治疗上首选机械通气治疗,并且无创机械通气并不是绝对禁忌证,值得推广。
Objective To analyze the curative effect of noninvasive mechanical ventilation and invasive mechanical ventilation on chronic obstructive pulmonary disease (COPD) complicated with pulmonary encephalopathy. Methods The clinical data of patients with COPD complicated with pulmonary encephalopathy admitted to Department of Respiratory Medicine, the First Affiliated Hospital of Xi’an Medical University from January 2010 to June 2011 were retrospectively analyzed. Patients treated with mechanical ventilation were selected according to different ways of mechanical ventilation Non-invasive group and invasive group, analysis of the two groups of treatment. Results After treatment, blood gas analysis was significantly improved in both groups, but there was no significant difference between the effective rate and the case fatality rate. At the same time, the complication of the non-invasive group was significantly lower than that of the invasive group. Conclusions The preferred mechanical ventilation for COPD patients with pulmonary encephalopathy and noninvasive mechanical ventilation are not absolute contraindications and should be promoted.