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目的利用横断面基线调查深圳市外来劳务工人血清中A群和C群流行性脑脊髓膜炎(流脑)水平,为外来劳务工人流脑防控提供依据。方法抽取深圳市罗湖区、龙岗区、宝安区3个监测点,每个监测点选择50人份以上,3个监测点共选择1003人,采用间接ELESA法(定量)检测血清中抗A群和C群脑膜炎奈瑟菌抗体效价。结果共检测1003份血清标本,外来劳务工人A群和C群流脑抗体平均滴度分别为10.78μg/ml、2.71μg/ml。A群和C群流脑血清抗体保护率分别为93.7%、64.8%,二者差异有统计学意义(P<0.01);不同年龄组、不同籍贯外来劳务工人A群流脑抗体保护率差异均有统计学意义(P<0.05)。结论深圳市外来劳务工人C群流脑抗体保护率明显低于A群,为了预防可能存在的流脑C群流行和暴发,提示应加强外来劳务工C群流脑多糖疫苗免疫接种。
Objective To investigate the level of serogroup A and C meningococcal meningitis in migrant workers in Shenzhen by cross-sectional baseline survey, and provide the basis for prevention and control of migrant workers. Methods Three monitoring sites were selected in Luohu District, Longgang District and Bao’an District of Shenzhen City. Each monitoring site was selected to have a population of 50 or more. A total of 1003 patients were selected from 3 monitoring sites. Anti-A and Group C meningitidis antibody titers. Results A total of 1003 serum samples were tested. The average titers of migrant workers in group A and group C were 10.78μg / ml and 2.71μg / ml, respectively. The antibody protection rates of group A and group C were 93.7% and 64.8% respectively, the difference was statistically significant (P <0.01). The antibody protection rates of group A meningitis antibody in different age groups and different native workers There was statistical significance (P <0.05). Conclusion The protection rate of C group meningitis antibody in migrant workers in Shenzhen is significantly lower than that in group A. In order to prevent the possible epidemic and outbreak of meningococcal C group, it is suggested that immunization of migrant workers should be strengthened.