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目的观察银杏达莫注射液对冠心病(CHD)患者PCI术后QT离散度(QTd)的影响,进一步探讨其临床应用价值。方法 216例冠心病接受PCI治疗患者,随机分为银杏达莫干预组112例,常规治疗组104例,分别测量两组患者手术前后及术后10d的QTd。同时测定对照者QTd。结果 (1)冠心病患者QTd较对照者明显延长,差异有统计学意义(P<0.05)。(2)两组患者PCI术后QTd明显缩短,差异有统计学意义(P<0.05)。(3)常规治疗组QTd术后10d较术后1d有下降趋势,但差异无统计学意义;银杏达莫干预组术后10d较术后1d QTd明显下降,差异有统计学意义。(4)术后10d,银杏达莫干预组较常规治疗组QTd明显缩短,差异有统计学意义。结论银杏达莫注射液可有效降低冠心病PCI术后患者的QTd,有很好的临床使用价值。
Objective To observe the effect of Yinxingdamo injection on QTd after PCI in patients with coronary heart disease (CHD) and to explore its clinical value. Methods A total of 216 patients with coronary heart disease undergoing PCI were randomly divided into two groups: 112 cases in the intervention group and 104 cases in the conventional treatment group. The QTd of the two groups before and after operation and after operation for 10 days were measured respectively. Control QTd was also determined. Results (1) QTd in patients with coronary heart disease was significantly longer than that in controls, the difference was statistically significant (P <0.05). (2) QTd of both groups were significantly shortened after PCI, the difference was statistically significant (P <0.05). (3) The QTd of conventional treatment group showed a downward trend 10d after operation compared with that of the 1st postoperative day, but the difference was not statistically significant. The QTd of the treated group was significantly lower than that of the 1st postoperative day 10d after operation, the difference was statistically significant. (4) On the 10th day after operation, the QTd of the Ginkgo biloba intervention group was significantly shorter than that of the conventional treatment group, the difference was statistically significant. Conclusion Ginkgo biloba injection can effectively reduce QTd in patients with coronary artery disease after PCI, and has good clinical value.