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目的对红波罗花Incarvillea delavayi全草的化学成分进行研究。方法采用90%乙醇进行回流提取,通过各种色谱技术对各部位进行分离,以各种光谱分析技术对分离化合物的结构进行鉴定。结果从红波罗花90%乙醇提取物中分离得到14个化合物,结构类型包括单萜生物碱、环己乙醇、三萜类等,分别鉴定为5-羟乙基-6-羟基-3-甲基苯并呋喃(1)、cleroindicin B(2)、3,4,5-三甲氧基苯甲酸乙酯(3)、3,4,5-三甲氧基苯甲酸甲酯(4)、6-羟基苯并二氢呋喃(5)、2-(4’-乙氧基苯基)-乙醇(6)、tecomine(7)、(+)-epidihydrotecomanine(8)、5-hydroxy skytanthine(9)、δ-skytanthine(10)、isoincarvilline(11)、mairine B(12)、coelobillardierine(13)、3β-乙酰基齐墩果酸(14)。结论化合物1为新化合物,命名为波罗花醇A;化合物3~6、9~11、13为首次从该植物中分离得到。
Objective To study the chemical constituents of the whole plant of Incarvillea delavayi. Methods 90% ethanol was used for reflux extraction. The constituents were separated by various chromatographic techniques and the structures of the isolated compounds were identified by various spectral analysis techniques. Results Fourteen compounds were isolated from the 90% ethanol extract of Rhododendron chinense. The structures of the compounds included monoterpene alkaloids, cyclohexanol and triterpenoids, which were identified as 5-hydroxyethyl-6-hydroxy-3- Methylbenzofuran (1), cleroindicin B (2), ethyl 3,4,5-trimethoxybenzoate (3), methyl 3,4,5-trimethoxybenzoate (6), tecomine (7), (+) - epidihydrotecomanine (8), 5-hydroxy skytanthine (9) , Δ-skytanthine (10), isoincarvilline (11), mairine B (12), coelobillardierine (13), 3β- acetyl oleanolic acid (14). Conclusions Compound 1 is a new compound named as poloxamer A. Compounds 3 ~ 6,9 ~ 11,13 were isolated from this plant for the first time.