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目的探讨输卵管积水对体外授精-胚胎移植(IVF-ET)结局的影响。方法选取2010年1—9月于唐山市妇幼保健院生殖遗传科行IVF-ET的患者120例,其中双侧输卵管积水未处理的30例作为研究组,同期因双侧输卵管积水行切除或离断术的40例及双侧输卵管阻塞的50例作为对照组,比较三组患者在促卵中卵巢的反应性及妊娠结局。结果①三组患者的年龄、不孕年限等一般资料比较差异无统计学意义(P>0.05)。②积水组的着床率、妊娠率低于对照组,异位妊娠率高于对照组,差异有统计学意义(P<0.05)。③输卵管积水处理后的着床率、妊娠率高于未处理组,异位妊娠率低于未处理组,差异有统计学意义(P<0.05)。结论输卵管积水的患者行IVF-ET助孕前行切除或离断术可明显提高妊娠率并降低异位妊娠发生率。
Objective To investigate the effect of hydrosalpinx on outcome of IVF-ET in vitro. Methods From January to September 2010, 120 cases of IVF-ET in Reproductive Genetics Hospital of Tangshan Maternal and Child Health Hospital were enrolled. Among them, 30 cases of untreated bilateral hydrosalpinx were selected as the study group, and resected by bilateral hydrosalpinx Or 40 cases of disconnection and 50 cases of bilateral tubal obstruction as a control group, ovarian response in ovulation and pregnancy outcome were compared among the three groups. Results ① There was no significant difference in general information such as age, duration of infertility among the three groups (P> 0.05). (2) The implantation rate and the pregnancy rate of the hydrocephalus group were lower than those of the control group, and the ectopic pregnancy rate was higher than that of the control group (P <0.05). ③ tubal hydronephrosis implantation rate, pregnancy rate was higher than untreated group, ectopic pregnancy rate was lower than the untreated group, the difference was statistically significant (P <0.05). Conclusions In patients with hydrosalpinx, resection or resection of IVF-ET can significantly improve the pregnancy rate and reduce the incidence of ectopic pregnancy.