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作者研究了短程强的松治疗对6例慢性乙型肝炎病人血清丙氨酸转氨酶水平(ALT)和HBV标记之影响。此6例皆为男性,年龄在25～33岁间,血清ALT53～328IU(正常<35IU),HBsAg、HBeAg和DNA聚合酶皆阳性。口服强的松60mg/天、40mg/天和20mg/天各2周。治疗期间和停药后观察期间每2周复查各项指标1次。结果6例中有5例在强的松60mg/天治疗后出现ALT水平明显下降。停药后ALT逐渐回升,20～67天后所有病人都反跳到比
The authors studied the effects of prednisone on serum levels of alanine aminotransferase (ALT) and HBV markers in 6 patients with chronic hepatitis B. All six cases were male, aged 25 to 33 years old, serum ALT53 ~ 328IU (normal <35IU), HBsAg, HBeAg and DNA polymerase were positive. Prednisone oral 60mg / day, 40mg / day and 20mg / day for 2 weeks. During treatment and withdrawal observed every 2 weeks during the review of the indicators 1 times. RESULTS: Of the 6 patients, 5 had a significant decrease in ALT levels following prednisone 60 mg / day treatment. After discontinuation of ALT gradually rose, 20 to 67 days after all patients rebound to more than