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本文观察１１３例男性不育症患者血清ＦＳＨ、ＬＨ和Ｔ含量的变化，结合实验室常规精液检测，分析了下丘脑－腺垂体－性腺轴体系统的功能活动和男性不育症相互关系。发现无精症患者血清ＦＳＨ和ＬＨ升高非常显著，而轻度少精症病人血清ＦＳＨ和ＬＨ浓度变化不明显。作者认为结合患者临床表现，测定血清多种生殖激素含量的改变，对于男性不育症的诊断和鉴别诊断具有重要的临床意义和参考价值。Ｐ＜０．０１；）男性不育少精症患者除重度少精症（精子数＜５００万／ｍｌ）病人血清ＦＳＨ显著升高以外，轻度少精症（精子数５００万～２０００万／ｍｌ）患者血清ＦＳＨ、ＬＨ和Ｔ含量均无明显改变（表２）。表２男性不育少精症患者血清ＦＳＨ、ＬＨ和Ｔ含量的变化（与正常对照组比较：＊Ｐ＜０．０５，；）３讨论在下丘脑－腺垂体－性腺（睾丸）轴体系统中，腺垂体分泌的促性腺激素包括ＦＳＨ和ＬＨ，它们不仅对女性性腺功能有促进作用，对雄性性腺（睾丸）的生精以及生精过程中所需的雄激素的产生都是必不可少的调节因素［４］。ＦＳＨ能够刺激睾丸支持细胞的生长、增植、成熟并诱导产生自身受体。而ＬＨ是睾丸间质细胞产生睾丸酮所必需的调节激素。它维持间质细胞的结构、数量和功能，并保持对其他激素产?
In this paper, the changes of serum FSH, LH and T levels in 113 male infertility patients were observed. The relationship between functional activity of hypothalamus-adenohypophyseal-gonadal axis system and male infertility was analyzed by routine laboratory tests. Found that patients with azoospermia serum FSH and LH increased very significant, and mild oligospermia serum FSH and LH concentrations did not change significantly. The authors believe that combined with the clinical manifestations of patients, determination of serum levels of a variety of reproductive hormones changes for the diagnosis and differential diagnosis of male infertility has important clinical significance and reference value. P <0.01). In addition to severe oligospermia (sperm count <5 million / ml), serum FSH was significantly increased in male infertility patients with oligozoospermia (sperm count of 5 million to 20 million / ml) serum FSH, LH and T content had no significant change (Table 2). Table 2 male infertility oligospermia serum FSH, LH and T changes (compared with the normal control group: * P <0.05 ,;) 3 Discussion in the hypothalamic-pituitary-gonad (testis) axis system , Gonadal pituitary gonadotropin secretion, including FSH and LH, they not only promote sexual function in women gonadal (testis) and spermatogenic process required for the production of androgen are essential Regulatory factors [4]. FSH stimulates the growth, proliferation, maturation of testicular support cells and induces their own receptors. And LH is testosterone necessary for testicular stromal cells regulate hormones. It maintains the structure, quantity and function of mesenchymal cells and maintains the production of other hormones?