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王镁老师认为痛风的发生主要责之于脾脏。先天禀赋不足，后天饮食不节，皆可损伤脾胃，致脾虚湿盛，郁而化热；若仍嗜食醇酒肥甘或复感外湿，内外湿邪胶着关节，湿热阻络，气滞血瘀，造成肢体关节红肿热痛，日久甚则变形失用。治当除湿清热，活血通络，调理脾胃。王老师以四妙散为基础方，自拟痛风方，分期辨证施治，随症加减，并适时应用西药，重视改良患者生活方式，在缓解疼痛及减少复发等方面取得了良好疗效。“,”WANG Mei thinks gout has the most close relationship with the spleen. Both the insufficient nat-ural endowment and the acquired improper diet can injure the spleen and stomach ,which lead to damp abundance due to spleen asthenia syndrome and heat results from stagnation. Excess intake of fatness and exogenous risk factors generate endogenous and exogenous pathogenic wetness integrating and adhering to limb joints. Dampness and heat cause Qi stagnation and blood stasis that induce the limb arthrosis red ,tu-mid,hot and painful,even deformed and apraxic after a long time. The therapeutic principles are removing damp-heat,activating blood circulation and regulating spleen and stomach. Teacher WANG uses self-made gout prescription based on Simiao powder to treat gout ,as modifies medicine according to syndrome differen-tiation and symptoms as well. Combined with western medicine and paying attention to improve patients ’ lifestyle,these therapies have achieved satisfactory clinical effect.