Mesenchymal stem cells improve the outcomes of liver recipients via regulating CD4＊T helper cytokine

• 作 者: Yang Yang Zhong-YangShen Bin W
• 机 构: FirstCentralHospitalClinicalCollege,DepartmentofOrganTransplantation
• 出 处: 国际肝胆胰疾病杂志：英文版
• 发表日期: 2016年3期
• 关键词: 骨髓间充质干细胞 肝移植 大鼠肝 细胞因子 患者 抑制活性 bone marrow mesenchymal stem cells liver transplan
• 基金项目: supported by grants from the National Natural Science Foundation of China(81270528 and 81441022),,Natural Science Foundation of Tianjin,China(08JCYBJC08400,11JCZDJC27800 and 12JCZDJC25200),,the Techno

BACKGROUND:Bone marrow mesenchymal stem cells(BMMSCs) exert immunosuppressive activities in transplantation.This study aimed to determine whether BMMSCs reduce acute rejection and improve outcomes of liver transplantation in rats.METHODS:Orthotopic liver