Clinical relationship between EDN-3 gene, EDNRB gene and Hirschsprung＇s disease

• 作 者: Xiang-LongDuan Xian-ShengZhang
• 机 构: DepartmentofGeneralSurgery,DepartmentofPediatricSurgery
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2003年12期
• 关键词: EDN-3基因 EDNRB基因 先天性巨结肠 PCR SSCP 发病机制
• 基金项目: 陕西省自然科学基金

AIM: To investigate the mutation of EDNRB gene and EDN3 gene in sporadic Hirschsprung's disease (HD) in Chinese population.METHODS: Genomic DNA was extracted from bowel tissues of 34 unrelated HD patients which were removed by surgery.Exon 3, 4, 6 of