The solute carrier transporters and the brain:Physiological and pharmacological implications

• 作 者: Chengliang Hu Lei Tao Xizhi Ca
• 机 构: SchoolofPharmaceuticalSciences,AdvancedInnovationCenterforHumanBrainProtection,CollaborativeInnovati
• 出 处: 亚洲药物制剂科学(英文)
• 发表日期: 2020年2期
• 关键词: SOLUTE carrier TRANSPORTER BRAIN DISORDER Blood-brain barrier Drug
• 基金项目: This work was supported by Nation Science and Technology Major Projects for Major New Drugs Innovation and Development(2018ZX09711003-004-002 to L.C.),Ministry of Science and Technology of China Natio

Solute carriers(SLCs)are the largest family of transmembrane transporters that determine the exchange of various substances,including nutrients,ions,metabolites,and drugs across biological membranes.To date,the presence of about 287 SLC genes have been id