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目的:探讨肾动脉狭窄的检出率及相关危险因素。方法:回顾性分析2003年1月至2005年1月期间我院1049例行冠状动脉造影并同时行肾动脉造影患者的临床资料及影像学资料。结果:(1)1049例患者中肾动脉显著性狭窄(直径狭窄≥50%)的检出率13.3%。564例冠心病患者肾动脉显著性狭窄的检出率20.7%,明显高于非冠心病患者。(2)单因素分析显示:肾动脉狭窄组与无肾动脉狭窄组比较,冠心病、冠状动脉钙化、陈旧心肌梗死、三支病变及高血压患者比例明显增高,低密度脂蛋白胆固醇水平、年龄也明显偏高。(3)高龄、高血清肌酐浓度水平、冠心病特别是三支冠脉病变患者有高的肾动脉狭窄检出率。(4)多因素Logistic回归显示:年龄、血清肌酐浓度、冠心病、三支冠脉病变是预测肾动脉狭窄的独立危险因子。结论:冠心病患者中肾动脉狭窄较常见,患者的临床特征能提示肾动脉狭窄。
Objective: To investigate the detection rate of renal artery stenosis and related risk factors. Methods: The clinical data and imaging data of 1049 coronary angiography patients undergoing renal artery angiography at our hospital from January 2003 to January 2005 were analyzed retrospectively. Results: (1) The detection rate of significant renal artery stenosis (diameter stenosis≥50%) in 1049 patients was 13.3%. 564 cases of coronary heart disease in patients with significant stenosis of the detection rate of 20.7%, significantly higher than non-coronary heart disease patients. (2) Univariate analysis showed that the proportion of patients with coronary artery stenosis, coronary artery calcification, old myocardial infarction, three-vessel disease and hypertension was significantly higher in patients with renal artery stenosis than those without renal artery stenosis. The levels of LDL-C, Also significantly higher. (3) elderly, high serum creatinine levels, coronary heart disease, especially in patients with three coronary artery lesions have a high detection rate of renal artery stenosis. (4) Multivariate logistic regression showed that age, serum creatinine concentration, coronary heart disease and three coronary artery lesions were independent risk factors for predicting renal artery stenosis. CONCLUSIONS: Renal artery stenosis is more common in patients with coronary artery disease and the clinical features of the patient are suggestive of renal artery stenosis.