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目的 评价化疗栓塞对四肢恶性骨肿瘤的治疗价值。方法 对14 例恶性骨肿瘤患者手术前行超选择插管化疗栓塞,并观察栓塞后并发症,研究肿瘤大体标本及组织学切片。结果 全部患者均有明显的栓塞后综合征(患肢明显肿胀、剧痛等),2 周后消失或明显减轻,1 例出现严重并发症皮肤坏死。栓塞后6 ~28 天,瘤体呈不同程度的凝固性坏死,肿瘤细胞属中度(60 % ) 以上坏死11 例。结论 化疗栓塞术能有效、安全地应用于四肢恶性骨肿瘤的治疗
Objective To evaluate the value of chemoembolization in the treatment of malignant bone tumors of extremities. Methods Fourteen patients with malignant bone tumors underwent superselective intubation and chemoembolization prior to surgery. Postoperative embolism was observed, and gross and histological sections of the tumor were studied. Results All patients had obvious post-embolism syndrome (significant limb swelling, severe pain, etc.), disappeared or significantly reduced after 2 weeks, and 1 patient had severe complications of skin necrosis. After embolization 6 to 28 days, the tumor showed varying degrees of coagulation necrosis, tumor cells were moderate (60%) or more necrosis in 11 cases. Conclusion Chemoembolization can be used effectively and safely in the treatment of malignant bone tumors of extremities