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目的分析浙江省诸暨市手足口病流行病学特征,为制定预防控制方案提供依据。方法对2008-2011年诸暨市手足口病监测资料及部分病例病原核酸检测资料进行分析。结果 2008-2011年共报告手足口病5273例,年平均发病率为99.89/10万,4-7月为发病高峰,9-10月出现小高峰;发病人群中散居儿童占59.34%,<5岁组占90.63%。聚集性疫情91起,幼托机构占94.51%;重症病例18例,死亡3例,0～2岁组占77.78%,以外地户籍儿童为主。病原学特征肠道病毒71型(EV71)感染占40.18%,柯萨奇病毒A组16型(Cox A16)感染占30.25%,其中重症病例和死亡病例以EV71感染为主;聚集性疫情以EV71和Cox A16感染为主,二者差异无统计学意义(P>0.05)。结论诸暨市手足口病的流行有明显地区、季节、人群特征,在手足口病监测和防控工作中,应根据手足口病的流行特点,关注流行高峰和重点人群,制定科学规范的防控预案。
Objective To analyze the epidemiological characteristics of hand, foot and mouth disease in Zhuji City, Zhejiang Province, and provide evidence for the development of prevention and control programs. Methods 2008-2011 hand-foot-mouth disease surveillance data in Zhuji City and some cases of pathogenic nucleic acid test data were analyzed. Results A total of 5273 hand-foot-mouth disease cases were reported in 2008-2011, with an average annual incidence of 99.89 / 100 000. The peak incidence was in April-July and a small peak in September-October. The incidence of diaspora in children was 59.34% The group accounted for 90.63%. There were 91 catching epidemics, 94.51% of which were nurseries, 18 were severe cases, 3 were dead, and 77.78% were from 0 to 2 years old. The etiological characteristics of enterovirus 71 (EV71) infection accounted for 40.18%, Coxsackie A group 16 (Cox A16) infection accounted for 30.25%, of which severe cases and deaths EV71 infection; aggregation epidemic to EV71 And Cox A16 infection, the difference was not statistically significant (P> 0.05). Conclusion The prevalence of hand-foot-mouth disease in Zhuji City is obviously regional, seasonal and crowded. In the monitoring and prevention and control of hand-foot-mouth disease, we should pay attention to the epidemic peak and key population according to the epidemic characteristics of hand-foot-mouth disease and formulate scientific and standardized prevention and control Plan.