论文部分内容阅读
为评价血清癌抗原 12 5(CA12 5)及抗子宫内膜抗体 (EmAb)水平对子宫内膜异位症 (内异症 )的诊断价值 ,以 87例需行腹腔镜或盆腔手术的住院患者为研究对象 ,其中内异症患者 (病例组 ) 71例 ,盆腔炎性包块患者 16例 (对照组 )。术前测定血清CA12 5及EmAb ,根据ROC方法确定CA12 5的最佳临界点。结果 :两组CA12 5及EmAb比较差别均无显著意义 (P >0 .0 5) ;CA12 5水平与美国生育协会的AFS分期无显著相关关系 (P >0 .0 5)。以 12 .5kU/L为临界点 ,单独测定血清CA12 5对诊断内异症的敏感性为 53.5% ,特异性为 56 .3%。单独测定EmAb诊断内异症的敏感性为 38.0 % ,特异性为 87.5%。联合二指标进行平行试验时 ,敏感性为 73.2 % ,特异性为 4 3.8% ;系列试验时敏感性为 18.3% ,特异性为 10 0 %。结论 :无论是单独还是联合运用血清CA12 5和EmAb均未能同时获得较好的敏感性和特异性
To assess the diagnostic value of serum CA12 5 and anti-endometrial antibody (EmAb) levels in endometriosis (endometriosis), 87 patients undergoing laparoscopic or pelvic surgery As the research object, 71 patients with endometriosis (case group) and 16 patients with pelvic inflammatory mass (control group). Preoperative determination of serum CA12 5 and EmAb, according to ROC method to determine the best critical point CA12 5. Results: There was no significant difference between the two groups of CA12 5 and EmAb (P> 0.05). There was no significant correlation between CA12 5 level and AFS stage of American Fertility Association (P> 0.05). With 12.5 kU / L as the critical point, the sensitivity of serum CA12 5 alone to diagnose endometriosis was 53.5% and the specificity was 56.3%. The sensitivity and specificity of EmAb for the diagnosis of endometriosis alone were 38.0% and 87.5% respectively. In parallel with the two indicators, the sensitivity was 73.2% and the specificity was 3.8%. The sensitivity and specificity of the series of tests were 18.3% and 100% respectively. CONCLUSIONS: Both CA125 and EmAb failed to achieve both good sensitivity and specificity either alone or in combination