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目的 探讨整蛋白型肠内营养治疗老年肝硬化型营养不良的临床疗效.方法 选取我院老年肝硬化患者96 例, 随机分成观察组48 例, 对照组48 例.所有患者进行营养评估, 对照组常规饮食, 观察组在对照组基础上服用整蛋白型肠内营养剂(55. 37 ± 16. 24) g/d, 温开水冲服.日常吃高维生素、易消化吸收食物, 使两组患者每日总热量达到30 ~35 kcal/kg, 蛋白质摄入1. 2 ~1. 5 g/kg, 详细记录每日摄入的总热量, 所有患者连续治疗24 周.比较两组患者治疗前后体重指数( Body mass index, BMI) 、白蛋白( Albumin, ALB) 、前白蛋白( Prealbumin, PA) 、凝血酶原活动度( Prothrombin Activity, PTA) 、淋巴细胞计数( Total lymphocyte count, TLC) .比较治疗前后水肿、腹水、 Child-Pugh分级和并发症发生情况.结果 治疗后, 观察组BMI、 ALB、 PA、 PTA分别高于对照组, 差异有统计学意义, P ＜0. 05; 观察组水肿无/轻中度、腹水无/轻中度、 Child -Pugh 为 B 级均明显高于对照组, 差异有统计学意义 P ＜0. 05; 观察组并发症肝性脑病、继发感染均明显低于对照组, 差异有统计学意义, P ＜0. 05.结论 整蛋白型肠内营养能够治疗肝硬化型营养不良、预防并发症、改善肝功能, 疗效确切.“,”Objective To explore the therapeutic effect of whole-protein enteral nutrition for elderly patients with liver cir-rhosis. Methods A total of 96 cases of elderly patients with cirrhosis in our hospital were selected. The patients were randomly di-vided into the control group (48 cases) and the observation group (48 cases). All patients were given nutritional assessment. The control group received a regular diet. The observation group received a regular diet and the whole protein type enteral nutrition agent (55. 37 ± 16. 24 g/d). Daily calories and protein intake were kept at (30~35) kcal/kg and (1. 2~1. 5 ) g/kg, respectively in two groups. Daily calories were recorded. All patients were treated for 24 weeks. Body mass index (BMI), albumin ( ALB), prealbu-min (PA), prothrombin activity (PTA), and total lymphocyte count (TLC) were measured before and after treatment. Edema, as-cites, child-pugh grading, and complications were recorded after treatment. Results After treatment, the values of BMI, ALB, PA and PTA in the observation group were higher than that in the control group (P＜0. 05). In the observation group, the ratios of patients with edema (no to moderate), ascites (no to mild), and the Child-Pugh (B grade) were significantly higher than those in the control group (P＜0. 05). The incidences of hepatic encephalopathy and secondary infection were significantly lower in the obser-vation group than those in the control group (P＜0. 05). Conclusion Whole protein type enteral nutrition is effective for treatment of liver cirrhosis, prevention of complications and improvement of liver function.