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目的探讨胎儿窘迫时静脉应用磷酸肌酸钠对新生儿血气的影响。方法选择2010年3月至2010年10月在焦作市妇幼保健院诊断为急性胎儿窘迫需剖宫产病例80例,随机分为两组,每组40例。实验组(A组)和对照组(B组),A组于术前静脉滴注磷酸肌酸钠1.0g;B组术前静脉滴注生理盐水100ml。分析比较新生儿出生后Apgar评分、脐静脉血气结果。结果 A组与B组相比:①新生儿出生后1min、5minApgar评分差异无统计学意义(P>0.05)。②脐静脉血pH值、pCO2、pO2差异均无统计学意义(P>0.05)。③脐静脉血HCO3_、BE值A组与B组相比差异有统计学意义(P<0.001﹚。结论急性胎儿窘迫剖宫产术前静脉滴注磷酸肌酸钠有利于胎儿能量代谢和利用,改善胎儿酸中毒,维持新生儿内环境的稳定。
Objective To investigate the effect of intravenous administration of sodium creatine phosphate on neonatal blood gas during fetal distress. Methods From March 2010 to October 2010, 80 cases of cesarean section were diagnosed as acute fetal distress in Jiaozuo MCH. They were randomly divided into two groups of 40 cases. In the experimental group (group A) and control group (group B), group A received preoperative intravenous infusion of 1.0 g of sodium creatine phosphate; Group B received intravenous infusion of 100 ml of normal saline. Analysis of neonatal Apgar score after birth, umbilical vein blood gas results. Results Compared with group B, there was no significant difference in Apgar score between 1 and 5 minutes after birth (P> 0.05). ② Umbilical vein blood pH, pCO2, pO2 differences were not statistically significant (P> 0.05). ③ The HCO3_ and BE values in umbilical cord blood were significantly different from those in group B (P <0.001). Conclusion Acute fetal distress before cesarean section intravenous infusion of sodium creatine phosphate is conducive to fetal energy metabolism and utilization, improve fetal acidosis and maintain the stability of the neonatal environment.