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目的 探讨先天性梅毒婴儿的中枢神经系统CT特征。方法 回顾性分析经临床确诊的11例先天性梅毒婴儿的中枢神经系统CT资料。结果 10例新生儿患者在CT上均表现为脑白质的弥漫性密度减低,其中3例合并有蛛网膜下腔出血, 1例合并有脑内出血。1例2个月大的患儿表现为两侧额、颞叶脑沟增宽及大脑镰前部蛛网膜下腔增宽, 5例经治疗后45d至6个月,CT复查表现为两侧脑沟、脑池、脑裂的增宽,其中3例伴有侧脑室和第3脑室的扩大。结论 先天性梅毒中枢神经系统的CT表现在新生儿类似重度缺氧缺血性脑病,随访复查可呈现外部性脑积水或脑发育不良的表现。
Objective To investigate the CT features of CNS in congenital syphilis infants. Methods The CT data of 11 cases of congenital syphilis infants diagnosed clinically were retrospectively analyzed. Results All 10 neonates showed diffuse densification of white matter on CT, including 3 cases of subarachnoid hemorrhage and 1 case of intracerebral hemorrhage. One case of 2-month-old children showed the amount of both sides of the temporal lobe sulci widened and the anterior cerebral anterior subarachnoid space widened, 5 cases 45d to 6 months after treatment, CT review showed both sides Sulci, brain pool, cracked brain widened, of which 3 cases with lateral ventricle and the enlargement of the third ventricle. Conclusion The CT manifestations of CNS in congenital syphilis are similar to severe hypoxic-ischemic encephalopathy in newborns. The follow-up examination can show the appearance of external hydrocephalus or brain dysplasia.