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木文报告1例59岁男性患者,因软弱乏力住院,体检见明显苍白,瘀点,脾肿大;实验室检查,白细胞计数259,000,原始细胞82%,白细胞碱性磷酸酶积分51,骨髓细胞高度增生,几乎均被原始细胞所占,该类原始细胞大小不等,浆少嗜碱,染色质细含有核仁,未见奥氏小体(Auer),糖元染色阳性,过氧化酶染色阴性,诊断为急性淋巴细胞性白血病,经长春新碱、强地松治疗,达到完全缓解,继以氨甲喋呤鞘内注射,脑部放疗,予防中枢神经系统白血病,并以6-MP,氨甲喋呤维持治疗,其间数次骨髓检查均属正常,9个月后患者白细胞计数增至30,000以上,早幼粒1～6
In a wooden case, a 59-year-old man was admitted to hospital because of weakness and was found to be pale, petechious and splenomegaly. Laboratory tests revealed a white blood cell count of 259,000, blast cells 82%, leucocyte alkaline phosphatase score 51, bone marrow cells Highly proliferated, almost all of the primitive cells, such primitive cells ranging in size, less basophilic pulp, chromatin containing nucleoli, no Au body, glycogen staining, peroxidase staining Negative, diagnosed as acute lymphoblastic leukemia, vincristine, prednisone treatment, to achieve complete remission, followed by intrathecal injection of methotrexate, brain radiotherapy, to prevent central nervous system leukemia, and 6-MP, methotrexate maintenance treatment , During which several bone marrow tests are normal, nine months after the patient’s white blood cell count increased to 30,000 or more promyelocytic 1 to 6