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目的:评估糖尿病肾病(DN)病人的营养状况,探讨其与血清胱抑素C(CysC)水平的相关性。方法:调查DN的住院病人73例,采用膳食调查、体格检查、实验室检查、主观全面性营养评估(SGA)法综合评价病人的营养状况,根据营养评价结果分为营养良好组(A组),轻-中度营养不良组(B组)和重度营养不良组(C组),所得数据经软件统计分析各组病人的CysC水平差异。结果:被调查DN病人中营养不良发生率为74.7%,血CysC水平与血红蛋白、清蛋白、肱三头肌皮皱厚度、淋巴细胞计数呈负相关。结论:DN病人的营养不良发生率较高,与DN肾功能损害程度、膳食结构不合理密切相关。其营养状况与血CysC水平存在相关性。DN病人血CysC水平升高者尽早进行营养干预,防止或减缓营养不良和其他并发症的发生。
Objective: To evaluate the nutritional status of patients with diabetic nephropathy (DN) and to explore its correlation with serum cystatin C (CysC) levels. Methods: 73 inpatients with DN were investigated. The nutritional status of patients was assessed by dietary survey, physical examination, laboratory examination and subjective comprehensive nutrition assessment (SGA). According to the nutritional evaluation results, the patients were divided into two groups: , Mild-moderate malnutrition group (group B) and severe malnutrition group (group C). The data were analyzed by software to analyze the difference of CysC level in each group. Results: The incidence of malnutrition in patients with DN was 74.7%. The level of serum CysC was negatively correlated with hemoglobin, albumin, trichoderma skin fold thickness and lymphocyte count. Conclusion: The incidence of malnutrition in patients with DN is higher, which is closely related to the extent of renal dysfunction and irrational dietary structure. The nutritional status and blood CysC levels are related. DN patients with elevated blood levels of CysC nutritional intervention as soon as possible to prevent or slow the occurrence of malnutrition and other complications.