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目的:观察调肝理肺汤合吸入性糖皮质激素治疗支气管哮喘的临床疗效。方法:将60例轻、中度支气管哮喘患者随机分为治疗组和对照组各30例,治疗组采用调肝理肺汤合吸入性糖皮质激素治疗,对照组单用吸入性糖皮质激素治疗。治疗3个月后比较两组临床疗效,检测治疗前后血小板活化因子(PAF)、肺功能、最大呼吸流量(PEF)昼夜波动率等。结果:总有效率治疗组为93.3%,对照组为83.3%,组间比较,差异有统计学意义(P<0.05);两组PAF、FEV1%、PEF昼夜波动率治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.05)。结论:调肝理肺汤联合吸入性糖皮质激素治疗支气管哮喘临床疗效及降低PAF、改善肺功能等方面优于单用吸入性糖皮质激素,值得在临床中推广应用。
Objective: To observe the clinical effect of Tiaoganlilu Decoction and inhaled glucocorticoid on bronchial asthma. Methods: Sixty patients with mild to moderate bronchial asthma were randomly divided into treatment group (30 cases) and control group (n = 30). Tiaoganlianfei decoction and inhaled glucocorticoid were used in treatment group and inhaled glucocorticoid alone . After 3 months of treatment, the clinical efficacy was compared between the two groups. The platelet activation factor (PAF), pulmonary function, maximum respiratory flow (PEF) diurnal fluctuation and so on were measured before and after treatment. Results: The total effective rate was 93.3% in the treatment group and 83.3% in the control group. There was significant difference between the two groups (P <0.05). The PAF, FEV1% After the comparison between groups, the differences were statistically significant (P <0.05). Conclusion: Tiaoganlianfei Decoction combined with inhaled corticosteroids in the treatment of bronchial asthma clinical efficacy and reduce PAF, improve lung function is superior to single inhaled corticosteroids, it is worth promoting in the clinical application.