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Verrlo“z”t和Coll等作者在1979年指出,通过皮下试验检查肌肉松弛剂之间可出现交叉过敏性反应。Flshez在1980年通过皮下注射肌肉松弛剂证实了这个事实。Baldo等在1983年指出,使用一种肌肉松弛剂后出现类过敏性休克反应时,在病人血清里产生一种对多种肌肉松弛剂有特异性的免疫蛋白,胺基根存在于所有的肌肉松弛剂和其他物质之中,例如消毒剂、美容剂、毛细血管代谢产物等。有些病人体内存在着多种箭毒类药物的抗体,尽管他们从未接触过这些物质。作者通过对二个病例的分析证明上述的事实。病例一,女性,17岁,于1980年注射三碘季胺酚后出现过严重的过敏性休克。
In 1979, authors such as Verrlo “z” and Coll pointed out that cross-allergic reactions may occur between muscle relaxants tested by subcutaneous testing. Flshez confirmed this fact in 1980 by injecting muscle relaxants subcutaneously. Baldo et al. (1983) pointed out that anaphylactic shock following a muscle relaxant produces an immune protein that is specific to various muscle relaxants in the patient’s serum, which is present in all muscles Relaxants and other substances, such as disinfectants, cosmetic agents, capillary metabolites and the like. Some patients have antibodies to a variety of arrow poisoning drugs, though they have never been exposed to these substances. The author proves the above facts by analyzing two cases. Case 1, female, 17 years old, had severe anaphylactic shock after injection of triiodide quaternary ammonium phenol in 1980.