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曾报道3例特发性肾病综合征（INS）用培氟沙星治疗后缓解，因而建议单用此药作为INS的一线治疗药物，而不首先使用皮质类固ny。Geffriaud－Ricouard等用其治疗6例INS未见有效，且不良反应发生率高。作者曾用培氟沙星治疗5～17岁儿童7例，其中6例为INS包括微小病变肾病（MCN）4
It has been reported that 3 patients with idiopathic nephrotic syndrome (INS) are treated with pefloxacin to relieve the disease. Therefore, it is recommended that this medicine should be used as the first-line treatment of INS without first using corticosteroid ny. Geffriaud-Ricouard and other 6 cases of INS treatment with no effective, and the incidence of adverse reactions. The authors treated pefloxacin in 7 children aged 5 to 17 years, of whom 6 were INS including minimal change nephropathy (MCN) 4