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目的:观察奥美拉唑、凝血酶治疗新生儿上消化道出血的治疗效果。方法:对我院2009年3月~2013年6月收治的83例新生儿上消化道出血的患儿,随机分为治疗组42例和对照组41例,两组患儿均给予积极治疗原发病,禁食,经口或经鼻插入胃管,用1.4%碳酸氢钠液洗胃,至洗出液转清亮为止,静脉滴注酚磺乙胺等,治疗组在上述治疗同时,采用胃管注入凝血酶,同时使用奥美拉唑静脉滴注;对照组使用奥美拉唑静脉滴注。结果:治疗组总有效率为95.2%,观察组总有效率为68.3%,两组比较,差异有统计学意义,P<0.01。结论:奥美拉唑、凝血酶联用治疗新生儿上消化道出血疗效显著,且不良反应少,值得推广应用。
Objective: To observe the therapeutic effects of omeprazole and thrombin in the treatment of neonatal upper gastrointestinal bleeding. Methods: 83 cases of neonates with upper gastrointestinal bleeding admitted to our hospital from March 2009 to June 2013 were randomly divided into treatment group (n = 42) and control group (n = 41). Both groups were given active treatment Incidence, fasting, oral or nasal tube insertion, gastric lavage with 1.4% sodium bicarbonate, to clear until the eluate to clear, intravenous infusion of phenylethylamine, the treatment group in the treatment at the same time, the use of Thrombin was injected into the gastric tube, while omeprazole was given intravenously. In the control group, omeprazole was given intravenously. Results: The total effective rate was 95.2% in the treatment group and 68.3% in the observation group. There was significant difference between the two groups (P <0.01). Conclusion: Combination of omeprazole and thrombin in the treatment of neonatal upper gastrointestinal bleeding has significant curative effect with less adverse reactions, which is worth popularizing and applying.