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1983年我们用吡喹酮治疗急性血吸虫病病人94例,其中男性83例,女性11例,年龄4~63岁,其中51例为15岁以下儿童。临床分型:轻型48例、中型30例、重型16例。全部病人治疗前粪便孵化血吸虫毛蚴阳性。 治疗方法 采用上海第十一制药厂生产的吡喹酮(批号830301)。儿童总剂量140mg/kg;成人为120mg/kg(以60kg为限),疗程6d,每天3次口服。治程中有一例重型加用激素改善症状。治前和治后10~14d检查肝功能42例。 观察结果 94例均按期足量完成疗程。药物副作用以头痛、头昏、腹痛、腹胀为主,反应均较轻,仅1例治后头昏、视力模糊、记忆力减退达一月以
In 1983, 94 patients with acute schistosomiasis were treated with praziquantel, including 83 males and 11 females, aged 4 to 63 years, 51 of whom were children under 15 years of age. Clinical classification: 48 cases of light, 30 cases of medium and heavy in 16 cases. Stool incubation before treatment of all patients Schistosome miracidia positive. Treatment with praziquantel produced in Shanghai No. 11 Pharmaceutical Factory (Lot 830301). Children total dose of 140mg / kg; adult 120mg / kg (60kg limit), course of treatment 6d, 3 times a day orally. A case of heavy plus hormone treatment to improve symptoms. Pre-and post-treatment 10 ~ 14d check liver function in 42 cases. The observation of 94 cases were completed on schedule full course of treatment. Drug side effects to headache, dizziness, abdominal pain, abdominal distension, the reaction was mild, only 1 case of dizziness, blurred vision, memory loss reached January