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目的 探讨甲基睾丸素用于药物流产的临床效果。方法 将 3 0 0例观察对象随机分为两组 ,每日早晚各服米非司酮 2 5mg,连服 3d ,观察组同时加服甲基睾丸素 10mg,每日 3次 ,连服 3d ,两组于第 4d早晨空腹服米索前列醇 0 .6mg。结果 观察组完全流产率 96% ,对照组 90 % ,具有显著差异(P <0 .0 5 ) ;阴道流血量观察组比对照明显减少 ,两组有极显著差异 (P <0 .0 1) ;阴道流血时间观察组比对照组明显缩短 ,两组有极显著差异 (P <0 .0 1)。结论 药物流产同时加服甲基睾丸素可以提高完全流产率 ,减少阴道流血量并缩短流血时间 ,迅速恢复月经周期。
Objective To investigate the clinical effect of methyltestosterone on medical abortion. Methods Three hundred and fifty subjects were randomly divided into two groups. Each morning and evening, mifepristone 25mg, even served for 3d, while the observation group plus methyltestosterone 10mg, 3 times a day, and even served 3d, Two groups on the 4th morning empty stomach misoprostol 0.6 mg. Results The rate of complete abortion was 96% in the observation group and 90% in the control group, with significant difference (P <0.05). The vaginal bleeding volume in the observation group was significantly lower than that in the control group, with significant difference between the two groups (P0.01) ; Vaginal bleeding time observation group was significantly shorter than the control group, the two groups were significantly different (P <0.01). Conclusions Both medical abortion and methyltestosterone can increase the rate of complete abortion, reduce vaginal bleeding and shorten the bleeding time, and resume menstrual cycle quickly.