【摘 要】
：
The phenylpyrazole insecticide fipronil blocks resistance to dieldrin (RDL)γ-aminobutyric acid (GABA) receptors in insects,thereby impairing inhibitory neuro-transmission.Some insect species,such as the diamondback moth (Plutella xylostella),possess more
【机 构】
：
State Key Laboratory for Conservation and Utilization of Subtropical Agro-BioresourceslKey Laborator
论文部分内容阅读
The phenylpyrazole insecticide fipronil blocks resistance to dieldrin (RDL)γ-aminobutyric acid (GABA) receptors in insects,thereby impairing inhibitory neuro-transmission.Some insect species,such as the diamondback moth (Plutella xylostella),possess more than one Rdl gene.The involvement of multiple Rdls in fipronil toxicity and resistance remains largely unknown.In this study,we investigated the roles of two Rdl genes,PxRdl1 and PxRdl2,in P xylostella fipronil action.In Xenopus oocytes,PxRDL2 receptors were 40 times less sensitive to fipronil than PxRDL1.PxRDL2 receptors were also less sensitive to GABA compared with PxRDL1.Knockout of the fipronil-sensitive PxRdl1 reduced the fipronil potency 10-fold,whereas knockout of the fipronil-resistant PxRdl2 enhanced the fipronil potency 4.4-fold.Furthermore,in two fipronil-resistant dia-mondback moth field populations,PxRdl2 expression was elevated 3.7-and 4.1-fold com-pared with a susceptible strain,whereas PxRdl1 expression was comparable among the resistant and susceptible strains.Collectively,our results indicate antagonistic effects of PxRDL1 and PxRDL2 on fipronil action in vivo and suggest that enhanced expression of fipronil-resistant PxRdl2 is potentially a new mechanism of fipronil resistance in insects.
其他文献
Segmentation of images with intensity inhomogeneity is a significant task in the field of image processing,especially in medical image processing and analysis.Some local region-based models work well on handling intensity inhomogeneity,but they are always
We consider the inverse problem of identifying a general source term,which is a function of both time variable and the spatial variable,in a parabolic PDE from the knowledge of boundary measurements of the solution on some portion of the lateral boundary.
In the present paper we study the well-posedness using the Galerkin method and the stabilization considering multiplier techniques for a fourth-order nonlinear Schr(o)dinger equation in domains with moving boundaries.We consider two situa-tions for the st
Let (W,S) be the affine Weyl group of type (B)2,on which we consider the length function e from W to N and the Bruhat order ≤.For y ＜ w in W,let μ(y,w) be the coefficient of q1/2(e(w)-e(y)-1) in Kazhdan-Lusztig polynomial Py,w ∈ Z[q].We determine some μ(y
Let G be an extension of a finite characteristically simple group by an abelian group or a finite simple group.It is shown that every Coleman automorphism of G is an inner automorphism.Interest in such automorphisms arises from the study of the normalizer
We study the relations between two groups related to cluster automorphism groups which are defined by Assem,Schiffler and Shamchenko.We establish the relation-ships among (strict) direct cluster automorphism groups and those groups consisting of periodici
Reed-Solomon codes are widely used to establish a reliable channel to transmit information in digital communication which has a strong error correction capability and a variety of efficient decoding algorithm.Usually we use the maximum likelihood decoding
Arylalkylamine N-acetyltransferase (aaNAT) catalyzes the acetylation of dopamine,5-hydroxy-tryptamine,tryptamine,octopamine,norepinephrine and other ary-lalkylamines to form respective N-acetyl-arylalkylamines.Depending on the products formed,aaNATs are i
Let R be an associative unital ring and not necessarily commutative.We analyze conditions under which every n × n matrix A over R is expressible as a sum A =E1 +…+ Es + N of (commuting) idempotent matrices Ei and a nilpotent matrix N.
For a group G,we produce upper and lower bounds for the sum of the entries of the Brauer character table of G and the projective indecomposable character table of G.When G is a π-separable group,we show that the sum of the entries in the table of Isaacs\