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目的观察和分析护理干预在胆囊结石患者应用腹腔镜手术治疗的护理效果。方法选取2013年10月~2014年10月进行胆囊切除的76例胆囊结石患者，随机分为两组。观察者38例患者，在围手术期给予综合性的护理方法；对照组38例患者，在围手术期给予常规的护理方法。比较两组患者的手术时间、出血量、住院时间、术后排气等指标。结果通过临床手术治疗并配合护理，观察者38例患者，总有效率94.74%(36/38)；对照组38例患者，总有效率81.58%(31/38)，观察组的总有效率优于对照组，两种护理方法有显著性差异，有统计学意义(<0.05)。结论通过对胆囊结石患者应用腹腔镜手术治疗围手术期中给予特殊的护理干预，临床效果好。“,”Objective To observe and analyze the nursing ef ect of nursing intervention in treatment of cholecystolithiasis patients laparoscopic operation.Methods From 2013 October to 2014 October 76 cases of gal stone patients with cholecystectomy,were randomly divided into two groups.Observation of 38 patients in peri operation period,given comprehensive nursing method;38 patients in the control group,routine nursing was given in peri operation period.Comparison of two groups of patients with operation time,amount of bleeding,hospitalization time,postoperative exhaust index.Results through the clinical operation treatment and nursing,the observation in 38 cases,the total ef iciency of 94.74%(36/38);38 patients in the control group,the total ef iciency of 81.58%(31/38),the total ef ective rate of observation group was bet er than that of the control group,two nursing methods have significant dif erence,with statistical significance ( <0.05).Conclusion Given nursing intervention on patients with cholecystolithiasis by special application of laparoscopic operation for the treatment of peri operation period,the clinical ef ect is good,worthy of clinical application.