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采用APAAP法,用小鼠抗大鼠T细胞表型的单抗测定抗喘药双奇保肺冲剂(以下简称“冲剂”)对大鼠外周血中T淋巴细胞亚群CD4细胞、CD8细胞数及CD4细胞与CD8细胞数的比值的影响,并测定对其免疫器官重量的影响。环磷酰胺(CY)为药物对照组。结果显示“冲剂”可显著降低被CY增高的大鼠CD8细胞数,明显增高被CY降低的CD4细胞与CD8细胞的比值。冲剂使大鼠脾脏重量及胸腺重量增加。结果表明:“冲剂”有增强免疫功能的作用。
Determination of CD4 cells and CD8 cell counts of T lymphocyte subsets in rat peripheral blood by anti-chuanchuan shuangqibao lung granules (hereinafter referred to as “granules”) using the monoclonal antibody against mouse T-cell phenotype using the APAAP method The effect of the ratio of CD4 cells to the number of CD8 cells, and the effect on the weight of their immune organs. Cyclophosphamide (CY) is a drug control group. The results showed that “granules” can significantly reduce the number of CD8 cells increased by CY and significantly increase the ratio of CD4 cells reduced by CY to CD8 cells. Granules increased spleen weight and thymus weight in rats. The results showed that “granules” have the effect of enhancing immune function.