论文部分内容阅读
本文调查了1988年至1993年间初治急性白血病住院病人125例,发生诱导期院内感染102例,感染率81.6%,102例院内感染病人死亡24例,因感染所致病死率为23.5%。感染部位以下呼吸道多见(49.0%),其次为败血症(12.8%)。本组细菌学检查阳性菌和阴性杆菌的构成比相似,革兰阳性球菌,尤其是表皮葡萄球菌有上升趋势。同时要及早注意是否有真菌感染的可能。化疗、激素和抗生素滥用及白细胞减少是感染增加的危险因素。本组分离所得的病原菌对常用抗生素基本耐药,表明急性白血病发生院内感染时应及时使用新一代抗生素,以免延误治疗。
This article surveyed 125 patients with newly diagnosed acute leukemia inpatients from 1988 to 1993. There were 102 cases of nosocomial infection during the induction period, the infection rate was 81.6%. Totally 24 patients died of 102 nosocomial infections. The mortality rate due to infection was 23.5%. Respiratory tract infection more common (49.0%), followed by sepsis (12.8%). This group of bacteriological positive bacteria and negative composition ratio of Bacillus, Gram-positive cocci, especially Staphylococcus epidermidis has an upward trend. At the same time as soon as possible to note whether there is the possibility of fungal infection. Chemotherapy, hormone and antibiotic abuse and leukopenia are risk factors for increased infection. The group of isolated pathogens on the basic antibiotic resistance, indicating that acute leukemia nosocomial infection should promptly use a new generation of antibiotics, so as not to delay treatment.