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目的探讨丹参川芎联合小剂量阿司匹林治疗急性脑梗死的预后。方法选取医院收治的急性脑梗死患者86例作为研究对象,采用数字随机对照表将患者分为对照组和观察组。对照组给予小剂量阿司匹林治疗,观察组在对照组基础上给予丹参川芎嗪注射液治疗。评估两组临床疗效,对比治疗前后血液流变学变化。结果观察组治疗有效率为88.37%,显著高于对照组(67.44%),差异具有统计学意义(χ2=5.47,P<0.05);观察组治疗后全血高切粘度、全血低切粘度、纤维蛋白原、血小板聚集率分别为(6.05±1.03)m Pa·s、(7.31±1.25)m Pa·s、(3.14±0.31)g/L、(0.46±0.11)%,显著低于对照组,差异具有统计学意义(均P<0.05)。结论丹参川穹嗪注射液联合小剂量阿司匹林治疗急性脑梗死,能够提高临床疗效,改善预后。
Objective To investigate the prognosis of acute cerebral infarction treated with Salvia Miltiorrhiza combined with low-dose aspirin. Methods Totally 86 patients with acute cerebral infarction admitted to hospital were selected as the research object. The patients were divided into control group and observation group by digital randomized controlled table. The control group was given low-dose aspirin, and the observation group was given Salviae Miltiorrhizae ligustrazine injection on the basis of the control group. The clinical efficacy of the two groups was evaluated, and the changes of hemorrheology before and after treatment were compared. Results The effective rate of observation group was 88.37%, significantly higher than that of control group (67.44%), the difference was statistically significant (χ2 = 5.47, P <0.05) (6.05 ± 1.03) mPa · s, (7.31 ± 1.25) mPa · s, (3.14 ± 0.31) g / L and (0.46 ± 0.11)% respectively, which were significantly lower than that of the control Group, the difference was statistically significant (all P <0.05). Conclusion Danshenvylidine injection combined with low-dose aspirin in the treatment of acute cerebral infarction can improve clinical curative effect and improve prognosis.