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本病临床报告极少,1986年以来国内报告三例,现将我科最近发现一例报告如下。患儿女,10个月,1993年5月20日就诊。出生后约5个月,面部发生数个米粒大红色丘疹,以后逐渐增多、变大,颜色也由红色变为黄红色和棕色。无烦躁不安,饮食、睡眠正常。患儿为第二胎足月顺产,父母非近亲结婚,家族成员中无类似发病史。发育、营养正常,系统检查心肺肝脾、胸透、血脂均正常。全身皮肤未发现咖啡色斑。整个面部散在分布大小不等之丘疹、结节、米粒大至黄豆大,计有180多个,丘疹为红色,结节呈半球形,红黄色或黄褐色,表面呈蜡样
The clinical report of the disease is extremely rare, and three cases have been reported domestically since 1986. A case report recently reported by our department has been found as follows. Children, 10 months, May 20, 1993. About five months after birth, several large red papules appear on the face, gradually increasing and becoming larger, and the color changes from red to yellowish red and brown. No irritability, normal diet and sleep. The child was born second-term childbirth, parents were not close relatives, and family members had no similar history. Development, normal nutrition, systemic examination of heart, lung, spleen, chest and blood lipids were normal. No brown spots were found on the whole body’s skin. The entire face is scattered in the size of the distribution of papules, nodules, rice grains to soy beans, including more than 180, papules are red, nodules were hemispherical, red yellow or brown, the surface was waxy