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本文通过对22例局部晚期乳腺癌术前动脉化疗与20例静脉化疗进行分析对照研究,探讨动脉灌注化疗在治疗局部晚期乳腺癌中的价值。 1 资料与方法一般资料:1994年2月至1995年3月我院收治女性原发局部晚期乳腺癌42例,按TNM分期(1988年修订)标准为Ⅱ_A期中T_3N_0M_0、Ⅲ_A、Ⅲ_B期而无远处转移者。非随机分试验组(动脉灌注化疗组)22例,对照组(静脉化疗组)20例。年龄30～65岁,平均43.4岁。两组的病期、肿瘤大小、部位、腋淋巴结情况、组织学类型、绝经情况基本相仿。治疗前检查:肿块经针吸或切取活检证实为乳腺癌,并行雌激素受体测定。乳腺癌块大小测定用触诊
In this article, 22 cases of locally advanced breast cancer undergoing preoperative arterial chemotherapy and 20 cases of intravenous chemotherapy were analyzed and compared to investigate the value of arterial infusion chemotherapy in the treatment of locally advanced breast cancer. 1 Materials and Methods General Information: From February 1994 to March 1995, 42 cases of primary locally advanced breast cancer were treated in our hospital. According to the TNM staging (revised in 1988), the T_3N_0M_0, III_A, and III_B phases in the II_A period were not far away. Transferred person. In the non-randomized experimental group (arterial infusion chemotherapy group) 22 cases, the control group (intravenous chemotherapy group) 20 cases. Age 30 to 65 years old, average 43.4 years old. The disease stage, tumor size, location, axillary lymph node status, histological type, and menopause were similar in both groups. Pre-treatment examination: The mass was confirmed by needle aspiration or biopsy as breast cancer, and the estrogen receptor was measured. Breast cancer size measurement with palpation