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用放射免疫法检测69例肝病患者血清睾酮(T)和雌二醇(E_2)水平,并以非肝病患者为对照。肝炎后肝硬化E_2水平最低,但与对照组及其他肝病组无显著性差异(P>0.05)。肝炎后肝硬化和重症肝炎的T水平显著低于对照组、急乙肝和慢迁肝。在肝硬化和重症肝炎患者中T<4.16nmol/L者多在一个月内死亡。提示T水平降低与肝损害严重程度及预后有一定关系。
The levels of serum testosterone (T) and estradiol (E 2) in 69 patients with liver disease were detected by radioimmunoassay, and compared with non-liver disease patients. The lowest level of E_2 was found in cirrhosis after hepatitis, but there was no significant difference between control group and other liver disease group (P> 0.05). Post-hepatitis cirrhosis and severe hepatitis T levels were significantly lower than the control group, acute hepatitis and chronic liver. In patients with cirrhosis and severe hepatitis T <4.16nmol / L were more than one month of death. Tip T level decreased with the severity of liver damage and prognosis have a certain relationship.