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对３０例系统性红斑狼疮（ＳＬＥ）患者（其中病情活动期者２０例，稳定期者１０例）血中自然杀伤细胞（ＮＫ细胞）活性、可溶性白细胞介素２受体（ｓＩＬ－２Ｒ）进行了检测，并与２０例正常对照者进行了比较研究，对二者的变化与ＳＬＥ病情变化的关系进行了分析。结果表明，ＮＫ细胞活性、ｓＩＬ－２Ｒ的变化是较血沉、抗双链脱氧核糖核酸（ＤＮＡ）抗体更灵敏、更有效的反映ＳＬＥ病情变化的指标，在对ＳＬＥ病情监测及指导治疗上具有重要意义。
Natural killer (NK) activity and soluble interleukin 2 receptor (sIL-2R) were measured in 30 patients with SLE (20 in active stage and 10 in stable stage) The test was compared with 20 normal controls, and the relationship between the changes and the changes of SLE was analyzed. The results showed that the changes of NK cell activity and sIL-2R were more sensitive and effective indicators of the changes of SLE than those of ESR and anti-double-stranded DNA (DNA) antibodies and were important in monitoring and guiding the treatment of SLE significance.