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[目的]掌握南京地区出入境人员梅毒和HIV感染的情况,探讨血清学诊断中的假阳性和假阴性,以便有针对性地开展传染病监测工作,并防止漏诊、误诊的发生。[方法]对24092名出入境人员进行了梅毒和HIV血清学检测。梅毒初筛试验采用不加热血清反应素试验(TRUST);确认试验采用梅毒螺旋体抗体血凝试验(TPPA)。HIV初筛试验采用酶联免疫吸附试验(ELISA);确认试验采用蛋白印迹法(WB)。[结果]梅毒感染19例,感染率为7.89/万(19/24092)。HIV感染者5例,感染率为2.08/万,另有HIV可疑感染者1例。[结论](1)南京地区出入境人员梅毒的感染率远远高于我国同期梅毒的感染率。(2)HIV感染主要以输入型为主。(3)应加强对出入境人员的监测力度,完善监督管理制度。(4)加强实验室建设,不断提高诊断水平和准确性,避免错检、漏检。
[Objective] To understand the situation of syphilis and HIV infection in entry-exit personnel in Nanjing, and to explore the false-positive and false-negative in serodiagnosis to carry out the surveillance of infectious diseases in a targeted manner and prevent the occurrence of misdiagnosis and misdiagnosis. [Methods] 24092 immigration officers were tested for syphilis and HIV serology. Syphilis screening test using unheated serum TRUST (TRUST); confirm the test using the Treponema pallidum antibody hemagglutination test (TPPA). HIV screening test using enzyme-linked immunosorbent assay (ELISA); confirm the test using Western blot (WB). [Results] 19 cases were infected with syphilis, the infection rate was 7.89 / (19/24092). 5 cases of HIV infection, the infection rate of 2.08 / million, while another case of HIV suspicious infection in 1 case. [Conclusion] (1) The prevalence of syphilis among immigration officers in Nanjing is much higher than that of syphilis in our country. (2) HIV infection mainly based on input type. (3) The monitoring of expatriates should be strengthened and the supervision and management system should be improved. (4) Strengthen laboratory construction, constantly improve diagnosis level and accuracy, avoid misjudgment and missed inspection.