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目的阐明准分子激光屈光性角膜切削术(PRK)后角膜内皮细胞的密度和核形态变化。方法 22只(40眼)新西兰白兔行-5.5OD,5.5mm 直径的近视 PRK,术后不同时期取角膜进行茜素红—锥蓝染色以观察角膜内皮细胞的密度和核形态。结果 PRK 术后角膜内皮细胞密度及核形态均无显著性改变。结论 PRK 对角膜内皮细胞无损害,是一项安全的矫正近视的方法。
Objective To clarify the density and nuclear morphological changes of corneal endothelial cells after excimer laser photorefractive keratectomy (PRK). Methods Twenty-two eyes (40 eyes) of New Zealand white rabbits underwent -5.5 OD with 5.5 mm diameter myopia PRK. The alveolar red-cone blue staining of the cornea was performed at different time points to observe the density and nuclear morphology of corneal endothelial cells. Results There was no significant change in corneal endothelial cell density and nuclear morphology after PRK. Conclusion PRK has no damage to corneal endothelial cells and is a safe method to correct myopia.