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收集人工引产或流产胚胎36例(胎龄为64天至8个月),取材自各标本的手指骨,其中尚有20例作了四肢及其他部位骨骺和骨端软骨的组织学切片。观察结果为:1.在胚胎的软骨组织内,不同程度地存在一些软骨细胞散在的退变消失现象及单个软骨细胞残影。2.坏死的软骨细胞可见单个,或者3～10个,有的形成小灶状。3.在部位分布上,增殖层表现比较明显。胎龄愈大,坏死细胞的检出率愈高。4.在残留的软骨细胞影子或细胞核碎片的周围,可见无细胞区及软骨巨细胞。作者认为,上述变化是一种轻微的、生理性的、一过性的形态学变化,甚至可能是一种必然要发生的改变,绝非是病理性的软骨细胞死亡。
Thirty-six cases of artificial abortion or abortion fetus (gestational age from 64 days to 8 months) were collected from the phalanges of each specimen, of which 20 were histological sections of epiphyseal and cartilage of the extremities and other parts. The results are as follows: 1. In the embryonic cartilage tissue, to some extent, there are some chondrocytes loose degeneration and disappearance of a single chondrocyte residual image. 2. Necrosis of chondrocytes visible single, or 3 to 10, and some form of small lesions. 3. In the distribution of parts, the proliferation of more obvious performance. The larger the gestational age, the higher the detection rate of necrotic cells. 4. In the residual chondrocyte shadow or nuclear debris around, visible acellular and cartilage giant cells. The author believes that the above change is a slight, physiological, transient morphological changes, and may even be an inevitable change, not by pathological chondrocyte death.