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食管静脉曲张出血是肝硬化门脉高压的危重并发症之一。出血的病死率高,二年累积出血病死率可达60%,住院期间约60%患者再次出血。经内镜硬化剂注射疗法(Endoscopic injection slerotherapy,EIS)能迅速控制急性大出血、降低死亡率并且不引起门体性脑病。因此,10余年来颇受青睐。但EIS的并发症发生率可达20~40%。一、EIS后食管病理变化硬化剂注射可引起一系列食管病理改变,其基本特征为:24小时内迅速形成静脉血栓、表浅粘膜坏死及中性粒细胞为主的炎性浸润,1月后炎症反应逐渐消散并
Esophageal varices bleeding is one of the critical complications of cirrhosis and portal hypertension. Bleeding mortality is high, two years cumulative hemorrhage mortality of up to 60%, about 60% of patients during hospitalization bleeding again. Endoscopic injection slerotherapy (EIS) provides immediate control of acute massive hemorrhage, reduces mortality, and does not cause portal encephalopathy. Therefore, more than 10 years popular. However, the complication rate of EIS can reach 20-40%. First, after esophageal pathological changes EIS sclerotherapy can cause a series of esophageal pathological changes, the basic features are: rapid formation of venous thrombosis within 24 hours, superficial mucosal necrosis and neutrophil-based inflammatory infiltration, after January Inflammation gradually dissipated