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目的探讨达英-35联合二甲双胍治疗多囊卵巢综合征的临床效果。方法将60例多囊卵巢综合症患者随机分为3组,分别予达英-35、二甲双胍、达英-35联合二甲双胍治疗3个周期,观察比较各项指标的变化。结果三组患者治疗后与治疗前比较,在BM I、WHR方面无明显差异;达英-35组治疗后T、LH、DHEAS明显降低及SHBG显著升高(P<0.05);二甲双胍组治疗后T、TC、TG、FBG、FINS明显降低及SHBG明显升高(P<0.05);联合用药组治疗后T、LH、DHEAS、TG、FBG、FINS均显著降低,SHBG水平显著升高(P<0.05)。结论达英-35与二甲双胍联合应用对多囊卵巢综合症具有更加全面的治疗效果。
Objective To investigate the clinical effect of da-Ying-35 combined with metformin in the treatment of polycystic ovary syndrome. Methods Sixty patients with PCOS were randomly divided into three groups. The patients were treated with Ying-35, metformin and da-Ying-35 combined with metformin for 3 cycles respectively. The changes of various indexes were observed and compared. Results After treatment, there was no significant difference in BM I and WHR between the three groups after treatment. The levels of T, LH, DHEAS and SHBG were significantly increased (P <0.05) The levels of T, TC, TG, FBG, FINS and SHBG were significantly decreased (P <0.05). The levels of T, LH, DHEAS, TG, FBG and FINS were significantly decreased and SHBG levels were significantly increased 0.05). Conclusion The combination of darling-35 and metformin has a more comprehensive therapeutic effect on PCOS.