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本文观察了镁盐、含镁极化液对实验性冠状动脉血栓形成致急性心肌梗塞时的血流动力学的影响,并分析了与血清离子浓度变化的关系。材料和方法1.动物模型及分组 对照组:用微量恒流恒压直流电刺激LAD外膜,建立犬冠状动脉血栓模型。镁盐治疗组(Mg组)和含镁极化液组(MgGIK组):犬6只,模型同对照组。在冠状动脉血栓形成后3小时,用MgSO_4200mg/kg加入10％Glucose500ml中静脉滴注至实验结束。MgGIK用量参见文献。2.血液动力学测定 经右股静脉插入7F导管人右心房采取血标本。同时插管测心输出量,以RM—6000型四道生理记录仪(日本光电)同步记录冠状动脉电刺激前(基础值),冠状动脉血栓形成后1、3、4、6小时的血流动力学各参数。主要血流动力学参数
In this paper, the effects of magnesium salt and magnesium-containing solution on the hemodynamics of experimental myocardial infarction with coronary artery thrombosis were observed. The relationship between serum magnesium concentration and serum ion concentration was also analyzed. MATERIALS AND METHODS 1. Animal model and group control group: Canine coronary thrombosis model was established by stimulating LAD outer membrane with a small amount of constant current and constant voltage direct current. Magnesium salt treatment group (Mg group) and magnesium polarization group (MgGIK group): 6 dogs, the model with the control group. Three hours after coronary thrombosis, 500 ml of MgSO_4200 mg / kg was added to 500 ml of 10% glucose to the end of the experiment. The amount of MgGIK see the literature. 2. Hemodynamic determination of the right femoral vein inserted into the right atrium by 7F catheter blood specimens. At the same time, the cardiac output of intubation was measured. The blood flow before coronary electrical stimulation (basal value), 1, 3, 4 and 6 hours after coronary thrombosis was simultaneously recorded by RM-6000 four-channel physiological recorder Kinetic parameters. The main hemodynamic parameters