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SAP起病急，病情凶险，病死率高。首诊医师需准确评估病情，建立多学科协调、转科或转院机制。病程早期需以器官维护、内科综合治疗为主。病程后期出现的感染性胰腺坏死、腹腔出血、胃肠道瘘等并发症的处理则提倡以微创干预为主导，必要时行外科手术治疗。恢复期间病因处理和预防复发、局部并发症、胰腺内外分泌功能不全等问题同样需多学科协作。以多学科团队为依托，对SAP患者进行全程管理，对提高急性胰腺炎治愈率、改善患者的生存质量具有重要意义。“,”Severe acute pancreatitis (SAP) is an acute severe disease with a high fatality rate. Initial doctor should accurately assess the disease severity and establish a multidisciplinary coordination and transfer plan. At the early stage, conservative medical treatment and organ support therapy are the main strategy. Minimally invasive intervention could be dominant in the management of complications such as infectious pancreatic necrosis, abdominal hemorrhage, gastrointestinal fistula and so on in the late course of the disease and surgical surgery could be administrated when necessary. During the recovery period, treatment of the etiologies, prevention of recurrence, local complications, and pancreatic endocrine and exocrine insufficiency also require multidisciplinary collaboration. Patient management of SAP through the whole course of the disease based on a multidisciplinary team is of great significance in increasing cure rate and improving quality of life.