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目的 探讨原发性支气管腺样囊性癌的临床、病理特征和治疗原则。方法 1980年1月～1997年5月手术治疗8例原发性支气管腺样囊性癌,均经手术和病理证实。结果 原发性支气管腺样囊性癌占同期原发性肺部恶性肿瘤的0.48％(8/1676);男性5例,女性3例;中心型6例,周围型2例;除1例肿瘤固定不能切除外,余7例均行手术切除,且其中4例存在癌残留。3年生存率为83.3％(5/6),5年生存率为60％(3/5)。结论 原发性支气管腺样囊性癌是一种罕见的低度恶性肿瘤,好发于主、叶支气管,X线表现与肺癌不易区别,纤维支气管镜检查最重要。目前认为手术切除是腺样囊性癌最有效的治疗方法,即便是姑息性切除,术后也能生存多年。
Objective To investigate the clinical, pathological characteristics and treatment principles of primary bronchial adenoid cystic carcinoma. Methods From January 1980 to May 1997, 8 cases of primary bronchial adenoid cystic carcinoma were surgically treated and confirmed by operation and pathology. Results Primary bronchial adenoid cystic carcinoma accounted for 0.48% (8/1676) of primary pulmonary malignancies at the same period; 5 males and 3 females; 6 patients with central type and 2 peripheral types; except 1 tumor. Unable to remove the fixed, the remaining 7 cases were all surgically removed, and 4 of them had cancer. The 3-year survival rate was 83.3% (5/6), and the 5-year survival rate was 60% (3/5). Conclusion Primary bronchial adenoid cystic carcinoma is a rare low-grade malignant tumor with predominance in the main and leaf bronchi. X-ray findings are indistinguishable from lung cancer. Fiberoptic bronchoscopy is the most important. Surgical resection is currently considered to be the most effective treatment for adenoid cystic carcinoma. Even palliative resection can survive for many years after surgery.